Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Systematic error for the methods across different exposures, considering the Optum EHR data source.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques:

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Uncalibrated Type 1 errors of methods as a function of time, across different exposures for the Optum EHR data source.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques:

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Calibrated type 1 errors of methods as a function of time, across different exposures for the Optum EHR data source.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques:

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Power of detection for the methods as a function of time, across different exposures for the Optum EHR data source. We assume the true risk ratio = 2.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques:

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet:

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques: Produced

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Systematic error for the methods, stratified across the two Covid-19 vaccines and the Optum EHR and MDCD data sources.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques: Vaccines

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Calibrated type 1 error for the methods as a function of time, stratified across the two Covid-19 vaccine exposures and the Optum EHR and MDCD data sources.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques:

Journal: medRxiv

Article Title: Comparative performance of the concurrent comparator design with existing vaccine safety surveillance approaches on real-world observational health data

doi: 10.64898/2026.01.25.26344812

Figure Lengend Snippet: Calibrated power of detection for the methods as a function of time, stratified across the two Covid-19 vaccine exposures and the Optum EHR and MDCD data sources.

Article Snippet: For this, we will consider the Optum EHR data source and exposure to both the BNT126b2 and mRNA-1273 COVID-19 vaccines, all seasonal flu vaccines, H1N1pdm vaccine, Zoster vaccine, and HPV vaccine.

Techniques: